What We Do Publications 2009 Publications

  1. Ayer, J.G., Harmer, J.A., Nakhla, S., Xuan, W., Ng, M.K., Raitakari, O.T., Marks, G.B. and Celermajer, D.S.(2009) HDL-Cholesterol, blood pressure, and asymmetric dimethylarginine are significantly associated with arterial wall thickness in children. Arterioscler Thromb Vasc Biol. 29(6):943-949. View Abstract.
  2. Ayer, J.G., Harmer, J.A., Xuan, W., Toelle, B., Webb, K., Almqvist, C., Marks, G.B. and Celermajer, D.S. (2009) Dietary supplementation with n-3 polyunsaturated fatty acids in early childhood: effects on blood pressure and arterial structure and function at age 8 years. Am J Clin Nutr. 90(2): 438-446. View Abstract.
  3. Baker, A.R., Harte, A.L., Pritlove, D.C., da Silva, N.F., Youssef, E.M., Khunti, K., Davies, M.J., Kumar, S., Pagano, D. and McTernan, P.G. (2009) Epicardial adipose tissue as a source of NFB and JNK mediated inflammation in patients with coronary artery disease. J Clin Endocrinol Metab. 94(1):261-267. View Abstract.
  4. Barter, P.J. (2009) Lessons learned from the investigation of lipid level management to its impact in atherosclerotic events. (ILLUMINATE) trial. Am J Cardiol 104 (suppl 10) 10e-15E.
  5. Bergman, A.J., Cote, J., Maes, A., Zhao, J.J., Roadcap, B.A., Sun, L., Valesky, R.J., Yang, A., Keymeulen, B., Mathijs, Z., De Smet, M., Laethem, T., Davies, M.J., Wagner, J.A. and Herman, G.A. (2009) Effect of sitagliptin on the pharmacokinetics of simvastatin. J Clin Pharmacol. 49(4):483-488. Abstract Unavailable.
  6. Cannon, C.P., Dansky, H.M., Davidson, M., Gotto, A.M. Jr, Brinton, E.A., Gould, A.L., Stepanavage, M., Liu, S.X., Shah, S., Rubino, J., Gibbons, P., Hermanowski-Vosatka, A., Bintowitz, B., Mitchel, Y. and Barter, P;DEFINE investigators.(2009) Design of DEFINE trial: determining the efficancy and tolerability of CETP inhibition with Anacetrapib. Am Heart J. 158(4): 513-519. e3. View Abstract.
  7. Carmel, J.F., Tarnus, E., Cohn, J.S., Bourdon, E., Davignon, J. and Bernier, L. (2009) High expression of apolipoprotein E impairs lipid storage and promotes cell proliferation in human adipocytes. J Cell Biochem.106(4):608-617. View Abstract.
  8. Chan, D.C., Lambert, G., Hugh, P., Barrett, B., Rye, K.A., Ooi, E.M.M. and Watts, G.E.(2009) Plasma proprotein convertase subtilisin/kexin type 9: a marker of LDL apolipoprotein B-100 Catabolism. Clin Chem. 55(11): 2049-2052. View Abstract.
  9. Chan, D.C., Watts, G.F., Ooi, E.M., Rye, K.A., Ji, J., Johnson, A.G. and Barrett, P.H.(2009) Regulatory effects of fenofibrate and atorvastatin on lipoprotein A-I and lipoprotein A-I:A-II kinetics in the metabolics syndrome. Diabetes Care. 32(11): 2111-2113. View Abstract.
  10. Chapman, A.L., Skaff, O., Senthilmohan, R., Kettle, A.J. and Davies, M.J.(2009) Hypobromous acid and bromamine production by neutrophils and modulation by superoxide. Biochem J. 417(3): 773-781. View Abstract.
  11. Chirovsky, D.R., Fedirko, V., Cui, Y., Sazonov, V. and Barter, P.J.(2009) Prospective studies on the relationship between high-density lipoprotein cholesterol and cardiovascular risk: a systematic review. Eur J Cardiovasc Prev Rehabil. 16(4): 404-423. View Abstract.
  12. Celermajer, D.S. and Chow, C.K. (2009) Concerning an Oversight. Atherosclerosis. 204(2):352. Abstract Unavailable.
  13. Davis, J.S., Yeo, T.W., Thomas, J.H., McMillian, M., Darcy, C.J., McNiel, Y.R., Cheng, A.C., Celermajer, D.S., Stephens, D.P. and Anstey, N.M. (2009) Sepsis-associated microvascular dysfunction measured by peripheral arterial tonometry: an observational study. Crit Care. 13(5): R155. View Abstract.
  14. Davies, M.J. (2009) Electron paramagnetic resonance detection of radicals in biology and medicine, in Electron Paramagnetic Resounce, Brustolon, M. and Giamello, E. eds. Hoboken, NJ. Wiley. 425-448.
  15. Dunlop, R.A., Brunk, U.T. and Rodgers, K.J.(2009) Oxidized proteins: mechanisms of removal and consequences of accumulation. IUBMB Life. 61(5):522-527. View Abstract.
  16. Fryirs, M., Barter, P.J. and Rye, K.A.(2009) Cholesterol metabolism and pancreatic beta-cell function. Curr Opin Lipidol. 20(3):159-164. View Abstract.
  17. Graves, L.E., Hennessy, A., Sunderland, N.S., Heffernan, S.J. and Thomson, S.E. (2009) Incidence of lymphoma in a captive-bred colony of hamadryas baboons (Papio hamadryas). Aust Vet 87, (6) 238-243.
  18. Groover, S.A., Kaouache, M., Joseph, L., Barter, P. and Davignon, J. (2009) Evaluating the incremental benefits of raising high-density lipoprotein cholesterol levels during lipid therapy after adjustment for the reductions in other blood lipid levels. Arch Intern Med 169 (19), 1775-1780.
  19. Gracanin, M., Hawkins, C.L., Pattison, D.I. and Davies, M.J.(2009) Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products. Free Radic Biol Med. 47(1):92-102. View Abstract.
  20. Hawkins, C.L. (2009) Role of hypothiocyanous acid (HOSCN) in biological systems. Free Rad Res 43 (12), 1147-1158.
  21. Hawkins, C.L., Morgan, P.E. and Davies, M.J. (2009) Quantification of protein modification by oxidants. Free Rad Biol Med. 46; 965-988. Abstract Unavailable.
  22. Hawkins, C.L., Pattison, D.I., Stanley, N.R. and Davies, M.J. (2009) Tryptophan residues are targets in hypothiocyanous acid-mediated protein oxidation. Biochem J. 416(3): 441-452. View Abstract.
  23. Ilsar, R., Chawantanpipat, C., Chan, K.H., Waugh, R., Hennessy, A., Celermajer, D.S. and Ng, M.K.(2009) The measurement of pulmonary flow researve in high order primates. Clin Exp Pharmacol Physiol. 36(8): 797-802. View Abstract.
  24. Kennett, E.C. and Davies, M.J.(2009) Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner:Implications for peroxynitrite-mediated damage at sites of inflammation. Free Radic Biol Med. 47(4): 389-400. View Abstract.
  25. Kyia, Y., Miura, S.I., Imaizumi, S., Uehara, Y., Matsuo, Y., Abe, S., Jimi, S., Urata, H., Rye, K.A. and Saku, K. (2009) Reconstituted high-density lipoprotein attenuates postinfarction left ventricular remodelling in rats. Atherosclerosis. 203(1):137-144. View Abstract.
  26. Lam, M.A., Pattison, D.I., Bottle, S.E., Keddie, D.J. and Davies, M.J. (2009) Nitric oxide and nitroxides can get as efficient scavangers of protein-derived free radicals. Chem Res Toxiol. 21(11):2111-2119. View Abstract.
  27. Lambert, G., Charlton, F., Rye, K.A. and Piper, D.E.(2009) Molecular basis of PCSK9 function. Atherosclerosis. 203(1):1-7. View Abstract.
  28. Laurila, P.P., Naukkarinen, J., Kristiansson, K., Ripatti, S., Kauttu, T., Silander, K., Salomaa, V., Perola, M., Karhunen, P.J., Barter, P.J., Ehnholm, C. and Peltonen, L. (2009) Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis. Arterioscler Thromb Vasc Biol 30 (2), 346-352.
  29. Ling, H., Waterworth, D.M., Stirnadel, H.A., Pollin, T.I., Barter, P.J., Kesaniemi, Y.A., Mahley, R.W., McPherson, R., Waeber, G, Bersot, T.P., Cohen, J.C., Grundy, S.M., Mooser, V.E. and Mitchell, B.D.(2009) Genome-wide linkage and association analysis to identify genes influencing adiponectin levels: The GEMS Study. Obesity (Silver Spring). 17(4): 737-744. View Abstract.
  30. Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Shields, B.J., Ooms, L.M., Stepto, N., Wu, B., Mitchell, C.A., Tonks, N.K., Watt, M.J., Febbraio, M.A., Crack, P.J., Andrikopoulos, S. and Tiganos, T. (2009) Reactive oxygen species enhance insulin sensitivity. Cell Metab 10 (4), 260-272.
  31. Maple-Brown, L.J., Cunningham, J., Barry, R.E., Leylsey, L., O'Rourke, M.F., Celermajer, D.S. and O'Dea, K. (2009) Impact of dyslipidaemia on arterial structure and function in urban indigenous Australians. Atherosclerosis. 202(1): 248-254. View Abstract.
  32. Marijon, E., Celermajer, D.S., Tafflet, M., El-Haou, S., Jani, D.N., Ferreira, B., Mocumbi, A.O., Paquet, C., Sidi, D. and Jouven, X. (2009) Rheumatic heart disease screening by echocardiography. The inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease. Circulation. 120(8): 663-668. View Abstract.
  33. McGrath, K.C., Li, X.H., Puranik, R., Liong, E.C., Tan, J.T., Dy, V.M., Di Bartolo, B.,Barter, P.J., Rye, K.A. and Heather, A.K.(2009) Role of 3-Hydroxysteroid-24 reductase in mediating anti-inflammatory effects of high-density lipoproteins in endothelial cells. Arterioscler Thromb Vasc Biol. 29(6): 877-882. View Abstract.
  34. McRobb, L., Handelsman, D.J. and Heather, A.K.(2009) Androgen-induced progression of arterial calcification in apolipoprotein E-null mice is uncoupled from plaque growth and lipid levels. Endocrinology. 150(2):841-848. View Abstract.
  35. Morgan, P.E., Sturgess, A.D. and Davies, M.J. (2009) Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients. Free Radic Res. 43(2): 117-127. View Abstract.
  36. Ng, M.K., Liu, P.Y., Williams, A.J., Nakhla, S., Ly, L.P., Handelsman, D.J. and Celermajer, D.S.(2009) Prospective study of effect of androgens on serum inflammatory markers in men. Arterioscler Thromb Vasc Biol. 22(7): 1136-1141. View Abstract.
  37. Peshavariya, H., Dusting, G.L., Di Bartolo, B., Rye, K.A., Barter, P.J. and Jiang, F. (2009) Reconstituted high-density lipoprotein suppresses leukocyte NADPH oxidase by activation by disrupting lipid rafts. Free Radic Res. 43(8): 772-782. View Abstract.
  38. Patel, S., Drew, B.G., Nakhla, S., Duffy, S.J., Murphy, A.J., Barter, P.J., Rye, K.A., Chin-Dusting, J., Hoang, A., Sviridov, D.,Celermajer, D.C. and Kingwell, B.A. (2009) Reconstituted high-density lipoprotein increases plasma high-density lipoprotein anti-inflammatory properties and cholesterol efflux capacity in patients with type 2 diabetes. J Am Coll Cardiol. 53(11):962-971. View Abstract.
  39. Patel, S., Puranik, R., Nakhla, S., Lundman, P., Stocker, R., Wang, X.S, Lambert, G., Rye, K.A., Barter, P.J., Nicholls, S.J. and Celermajer, D.S. (2009) Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high-density lipoproteins. Atherosclerosis. 204(2): 424-428. View Abstract.
  40. Rees, M.D., Bottle, S.E., Fairfull-Smith, K.E., Malle, E., Whitelock, J.M. and Davies, M.J. (2009) Inhibition of myeloperoxidase-mediated hypochlorous acid production by nitroxides. Biochem J. 421(1): 79-86. View Abstract.
  41. Pattison, D.I., Hawkins, C.L. and Davies, M.J. (2009) What are the plasma targets of oxidant hypochlorous acid? A kinetic modeling approach. Chem Res Toxicol. 22(5): 8007-817. View Abstract.
  42. Rodgers, K.J., Ford, J.L. and Brunk U.T.(2009) Heat Shock proteins: keys to healthy ageing? Redox Rep. 14(4): 147-153. View Abstract.
  43. Royle, C., Lim, S., Xu, B., Tooher, j., Ogle, R. and Hennessy, A. (2009) Effect of hypoxia and exogenous lL-10 on the pro-inflammatory cytokine TNF-alpha and the anti-atherogenic molecule soluble Flt-1 in placental villous explants. Cytokine 47(1): 56-60. View Abstract.
  44. Rye, K.A., Bursill, C.A., Lambert, G., Tabet, F. and Barter, P.J. (2009) The metabolism and anti-atherogenic properties of HDL. J Lipid Res (50) S195-200. Abstract Unavailable.
  45. Schwartz, G.G, Olsson, A.G., Balantyne, C.M., Barter, P.J., Holme, I.M., Kallend, D., Leiter, L.A., Leitersdorf, E., McMurray, J.J., Shah, P.K., Tardiff, J.C., Chaitman, B.R., Duttlinger-Maddux, J: dal-OUTCOMES Committees and Investigators (2009) Rationale and design of the dal-OUTCOMES trial: efficacy and safety of dalcetrapib in patients with recent acute coronary syndrome. Am Heat J. 158(6): 896-901. View Abstract.
  46. Seki, E., De Minicis, S., Gwak, G.Y., Kluwe, J., Inokuchi, S., Bursill, C.A., Llovet, J.M, Brenner, D.A. and Schwabe, R.F. (2009) CCR1 and CCR5 promote hepatic fibrosis in mice. J Clin Invest 19, (7) 1858-1870.
  47. Skaff, O., Pattison, D.I. and Davies, M.J.(2009) Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: Absolute rate constants and assessment of biological relevance. Biochem J. 422(1): 111-117. View Abstract.
  48. Strychar, I., Cohn, J.S., Renier, G., Rivard, M., Aris-Jilwan, N., Beauregard, H., Meltzer, S., Belanger, A., Dumas, R., Ishac, A., Radwan, F. and Yale, J.F. (2009) Effects of a higher-carbohydrate/lower-fat diet versus a lower-carbohydrate/higher-fat-monounsaturated diet on postmeal triglyceride concentrations and other cardiovascular risk factors in Type 1 Diabetes. Diabetes Care. 32(9): 1597-1599. View Abstract.
  49. Tabet, F. and Rye, K.A. (2009) High-density lipoproteins, inflammation and oxidative stress. Clin Sci (Lond). 116(2): 87-98. View Abstract.
  50. Tabet, F., Remaley, A.T., Segaliny, A.I., Millet, J., Yan, L., Nakhla, S., Barter, P.J., Rye, K.A. and Lambert, G. (2009) The 5A apolipoprotein A-I mimetic peptide displays anti-inflammatory and anti-oxidant properties in vivo and in vitro. Arterioscler Thromb Vasc Biol 30, (2) 246-252.
  51. Tandy, S., Chung, R.W., Wate, E., Kamili, A., Berge, K., Griinari, M. and Cohn, J.S.(2009) Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high fat fed mice. J Agric Food Chem. 57(19): 9339-9345. View Abstract
  52. Taskinen, M.R., Sullivan, D.R., Ehnholm, C., Whiting, M., Zannino, D, Simes, R.J., Keech, A.C. and Barter, P.J.; for the FIELD study investigators(2009) Relationships of HDL Cholesterol, ApoA-I and ApoA-II with homocysteine and creatinine in patients with type 2 Diabetes treated with fenofibrate. Arterioscler Thromb Vasc Biol. 29(6): 950-955. View Abstract.
  53. Wat, E., Tandy, S., Kapera, E., Kamili, A., Chung, R.W., Brown, A., Rowney, M. and Cohn, J.S.(2009) Dietary phospholipid-rich dairy milk reduces hepatomegaly, hepatic steatosis and hyperlipidemia in mice fed a high-fat diet. Atherosclerosis. 205(1): 144-150. View Abstract.
  54. Wu, B.J., Midwinter, R.G., Cassano, C., Beck, K., Wang, Y., Changsiri, D., Gamble, J.R. and Stocker, R. (2009) Heme oxygenase-1 increases endothelial progenitor cells. Arterioscler Thromb Vasc Biol 29 (10), 1537-1542.
  55. Xu, B., Thornton, C., Tooher, J., Ogle, R., Lim, S., Makris, A. and Hennessy, A.(2009) Anti-hypertensive drugs effect on SFLT-1 and sendoglin production from human normal and preeclamptic placentas in-vitro. Clin Exp Pharmacol Physiol. 36(8): 839-842. View Abstract.
  56. Xu, B., Thornton, C., Tooher, J. and Hennessy, A. (2009) Exogenous soluble VEGF receptor-1 (sFlt-1) regulates Th1/Th2 cytokine production from normal placental explants via intracellular calcium. Hypertens Pregnancy 28 (4), 448-456.
  57. Yeo, T.W., Lampah, D.A., Tjitra, E., Gitawati, R., Kenangalem, E., Piera, K., Granger, D.L., Lopansri, B.K., Weinberg, J.B., Price, R.N., Duffull, S.B., Celermajer, D.S. and Anstey, N.M.(2009) Relationship of cell-free hemoglobin to impaired endothelial nitric oxide bioavailability and perfusion in severe falciparum malaria. J Infect Dis. 200(10):1522-1529. View Abstract.
  58. Zerrad-Saadi, A., Therond, P., Chantepie, S., Couturier, M, Rye, K.A., Chapman, M.J. and Kontush, A.(2009) HDL 3-mediated inactivation of LDL-associated phospholipid hydroperoxides is determined by the redox status of apolipoprotein A-I and HDL particle surface lipid rigidity. Relevance to inflammation and atherosclerosis. Arterioscler Thromb Vasc Biol. 29(12):2169-2175. View Abstract.