The regenerative power of stem cells

While treatments for arterial blockages have previously been very limited, our new stem cell research is demonstrating that it’s actually possible for the body to grow new blood vessels. Not only that, these blood vessels can substantially increase blood flow. 

Having successfully demonstrated this in the lab, the Cell Therapeutics Group is continuing to build an understanding of the method, which is providing hope for millions of people worldwide.

The process involves introducing blood vessel lining cells derived from induced pluripotent stem cells, known as ISPCs. The ISPCs are adult skin cells ‘reprogrammed’ to become other cell types, meaning they are not embryonic stem cells taken from unborn babies. This is just some of the awe-inspiring ork taking place every day at the Heart Research Institute.

The Cell Therapeutic Group’s overall focus is to develop novel therapies targeted against atherosclerosis (arterial blockages) and its consequences, namely the reduction in blood flow to the heart and periphery, leading to heart attack and stroke.

Their treatment aim is to bypass arterial blockages by stimulating new blood vessel growth, to restore blood flow to affected regions.

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