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Every day brings us closer to finding a cure for cardiovascular disease - the UK's number one killer. Here is the latest from our research laboratories.
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HRI scientists pursue implant ‘Holy Grail’

HRI scientists pursue implant ‘Holy Grail’

In a world-first discovery, scientists at the Heart Research Institute have developed a high-tech coating that regulates the body’s often severe immune response to synthetic implants. This brings us one step closer to an exciting future where the human body does not reject lifesaving coronary bypass implants. 

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Smart new nanoparticle makes good drugs brilliant

Smart new nanoparticle makes good drugs brilliant

Scientists at Heart Research Institute have engineered multifunctional nanoparticles that can effectively work as ‘nanocarriers’, hauling a wide range of molecules including drugs or genetic material, to exactly where it needs to go in the body. These super-charged nanoparticles with truck-like power and GPS-style precision are poised to change the way medication is delivered to sick Australians.

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Silk mends broken hearts

Silk mends broken hearts

The world’s most luxurious fabric could soon be used to weave blood vessels that offer life to heart bypass patients, a breakthrough HRI study has found. Scientists at HRI in Sydney built and tested silk blood vessels and discovered they’re more effective and better tolerated than synthetic materials currently used in Australian hospitals. 

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Crystal ball molecule predicts diabetes before it strikes

Crystal ball molecule predicts diabetes before it strikes

HRI researchers have developed a simple test to predict diabetes more than a decade before it strikes, a breakthrough that could help ease the impending diabetes epidemic. The team has uncovered an important molecule found in liver fat that can identify who is most at risk of developing diabetes and other cardio-metabolic disorders like liver disease.  

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New drug hope to target silent killer

New drug hope to target silent killer

An exciting new treatment for very high blood pressure is on the horizon after a world-first discovery by Heart Research Institute scientists, who have uncovered a brain chemical instrumental in triggering hypertension, the so-called silent killer responsible for the deaths of thousands of Australians each year.

The researchers are optimistic the results, published this week in the American Journal of Physiology-Heart and Circulatory Physiology, will ultimately lead to a powerful new treatment that blocks a neurotransmitter and frees patients from the dangers of hypertension. 

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