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Every day brings us closer to finding a cure for cardiovascular disease - the UK's number one killer. Here is the latest from our research laboratories.
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Professor Shaun Jackson

HRI researchers discover how biomechanical thrombus growth is mediated

HRI researchers discover how biomechanical thrombus growth is mediated

Following injuries like a nick or cut, platelets that utilise the binding and signaling functions of an integrin called glycoprotein IIb/IIIa, or αIIbβ3, swarm the wound and clump together, forming a ‘plug’ or clot to stop blood loss. This first stage of wound healing is called hemostasis. However, this clumping of platelets can also cause deadly blood clots – thrombosis – which can lead to cardiovascular disorders such as heart attack or stroke.

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Blood clot breakthrough a saviour for diabetics

Blood clot breakthrough a saviour for diabetics

A breakthrough by HRI scientists could soon protect tens of thousands of Australians with diabetes from killer heart disease and stroke.

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The life and death of platelets

The life and death of platelets

Professor Shaun Jackson is interviewed about his work on ‘Proinflammatory Function of Dying Platelets’ at the International Society on Thrombosis and Haemostasis (ISTH) 2017 Congress in Berlin, Germany. 

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