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Advances in material fabrication techniques and 3D printing in micro and nanotechnology have revolutionised bioengineering, allowing high precision manipulation of materials for modelling medical systems and devices in the lab.

Using these strategies, biomimetic in vitro model systems can be generated to recreate physiological conditions to evaluate medical device materials, geometries and drugs.

Device failure mechanisms and how different disease states progress can be investigated with the aim of developing new treatments or preventative therapies.