Dr Sergey Tumanov PhD

Dr Tumanov received his degree in bioanalytical chemistry from Belarussian State University, Minsk. In 2011 he was invited to undertake his PhD at University of Auckland, New Zealand, where he utilised a metabolomics approach to study yeast metabolism during fermentation. In 2014, Dr Tumanov joined Dr Jurre Kamphorst’s laboratory at the Beatson Institute for Cancer Research in Glasgow, UK, where he worked as a postdoctoral research scientist on the utilization of ¹³C- and ²H-tracing and mass spectrometry-based -omics techniques to study lipid metabolism in cancer. This work was focused on better understanding the mechanisms underlying the high adaptability of cancer cells to oxygen- and nutrient-deprived (‘tumour-like’) conditions. In 2018, he joined Professor Roland Stocker’s laboratory at the Victor Chang Cardiac Research Institute, where he worked with an in vivo tandem stenosis model of plaque instability on the genetic background of ApoE deficiency. In 2019, Dr Tumanov received a Cardiac and Vascular Health Clinical Academic Group E/MCR Seed Grant (Chief Investigator). In 2020, Dr Tumanov moved to the Heart Research Institute. His research focus is on: i) understanding the role of myeloperoxidase in causing unstable atherosclerotic plaque; ii) understanding the metabolic alterations that lead to the formation of unstable atherosclerotic plaque; and iii) discovering new molecular imaging targets and biomarkers that distinguish stable from unstable atherosclerotic plaque utilising a multi-omics approach (metabolomics/lipidomics/proteomics/fluxomics).