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The 12 most common heart and cardiovascular conditions and what you can do about them

Heart and cardiovascular conditions can be life-changing. Understand the impact of these common conditions, and find out what you can do about them.

Heart and cardiovascular conditions are among the most common in the world.

The umbrella term cardiovascular disease (CVD) refers to all the diseases of the cardiovascular system – which consists of the heart and all the blood vessels in the body.

CVD is the leading cause of death globally. Every year, an estimated 17.9 million lives are lost to CVD.

The stages of atherosclerosis

Coronary heart disease

Coronary heart disease is a common condition where the major blood vessels to the heart – the coronary arteries – become blocked and narrowed, restricting the flow of blood to the heart. Coronary heart disease is also known as coronary artery disease.

The main underlying cause of coronary heart disease is atherosclerosis. This is the process by which fat, cholesterol and other substances build up and form plaque in the arteries. If this occurs in the coronary arteries, the plaque can form a blood clot (thrombosis) that restricts the flow of oxygen-rich blood to the heart. Without enough oxygen, the heart cannot function properly, and chest pain (angina) may result. If a blood clot blocks or stops the flow of blood to the heart, it can cause a heart attack.

Coronary heart disease often develops over time. Fatty deposits may develop in the arteries in earlier years and then thicken and build up as the person ages.

In heart failure, the heart muscle may become damaged and weak, and unable to pump enough blood around the body.

High blood pressure

High blood pressure is very common, with one in three Australian adults living with it.

Also known as hypertension, high blood pressure is when the force of the blood against the artery walls is higher than normal for an extended period of time or the long term. This puts a strain on the arteries, and the heart also has to work harder to keep blood circulating around the body.

High blood pressure is a cause for concern because it can damage the arteries over the long term and is a major risk factor for CVD. It can also cause damage to important organs in the body, such as the brain and kidneys. It’s important to regularly check blood pressure levels so that high levels can be appropriately managed.

How to identify and manage heart and cardiovascular conditions

Different heart and cardiovascular conditions will show different symptoms and be treated or managed in varying ways. It is important to speak to a healthcare professional if you experience symptoms that concern you or have any other concerns about your heart health.

Atrial fibrillation

Atrial fibrillation (AF) may not cause any symptoms, or the symptoms may only occur some of the time. AF can remain undetected for long periods of time, which is why it is so important to screen for AF.

Common symptoms of AF include:

  • heart palpitations
  • racing or ‘fluttering’ heartbeat
  • irregular heartbeat, which can be detected by checking the pulse
  • pain or discomfort in the chest (angina)
  • breathlessness, especially during activity
  • dizziness and light-headedness
  • tiredness and weakness.

While only your doctor can diagnose AF, you can keep an eye on your heart health by regularly checking your pulse. Keeping a record will help you notice if there is anything different or unusual with your results. Once AF has been diagnosed, medication and other treatments may be prescribed.

Stroke

Stroke can cause permanent or temporary disabilities, and in some cases can be fatal. The longer that a stroke remains untreated, the greater the chance of brain damage and lasting complications. The body parts that are controlled by the damaged areas of the brain will be affected and show signs of stroke.

The most common signs and symptoms of stroke are:

  • facial weakness
  • arm weakness
  • difficulty with speech.

The signs and symptoms of stroke may occur alone or in combination. They can last a few seconds or even up to 24 hours and then disappear.

An easy way to recognise and remember the signs of stroke is to use the FAST test. If someone is showing these symptoms, immediately seek emergency medical treatment.

  • Face: Check whether their facial features, such as their mouth, have drooped.
  • Arms: Can they lift both arms?
  • Speech: Are they having difficulty speaking, eg, slurring their speech? Can they understand you?
  • Time: Time is critical if you see any of the above signs. Call emergency services immediately.

Over 90 per cent of people who have a stroke remain without effective treatment, as the only clinically approved drug to treat ischaemic stroke can be used in only a small percentage of patients due to its severe side effects. To address this urgent need, HRI is conducting a world-first trial of a new anti-clotting drug that could potentially be used in all people who suffer a stroke.

How is HRI fighting common heart and cardiovascular conditions?

HRI is investigating new ways to prevent, detect and treat common heart conditions and CVD from a variety of different angles.

Our Atherosclerosis and Vascular Remodelling Group focuses on identifying and gaining insights from the genetic and molecular pathways involved in the build-up of plaque in atherosclerosis. These pathways could be used to improve treatments for atherosclerotic plaque.

Our Cardiovascular-protective Signalling and Drug Discovery Group is investigating how to repurpose existing drugs for next-generation therapies for cardiovascular diseases.

Our Clinical Research Group is conducting research into congenital heart disease (CHD), with a focus on young adults living with CHD. Research conducted by the group includes projects designed to improve quality of life and exercise capacity for people living with CHD; improve health outcomes in CHD for young adults, their families and the health system; and establish a unique National Congenital Heart Disease Registry.

Our Coronary Diseases Group is investigating whether the anti-inflammatory drug colchicine can be repurposed to protect against repeat heart attacks. This drug has already proved safe and effective for treating conditions like arthritis and gout.

Our Heart Rhythm and Stroke Prevention Group is investigating how best to screen at scale for atrial fibrillation (AF), which is linked to one third of strokes, to prevent as many strokes as possible.

Our Vascular Complications Group aims to understand the pathogenesis of blood vessel disease in diabetes, and using this knowledge, identify new strategies to improve function and reduce the burden of disease.

Our Vascular Immunology Group focuses its research on better understanding preeclampsia and its impact, as well as the development of new drug treatments for preeclampsia. Preventing preeclampsia could help prevent or reduce the risk of future CVD in women.

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